Post-Metachronous Cancer of the Ampulla of Vater after Gastric Cancer Surgery: An Overview

Authors

  • Mehmet Yildirim Department of General Surgery, University of Health Sciences Turkey, Izmir Bozyaka Education and Research Hospital, Turkey.
  • Erkan Oymaci Department of General Surgery, University of Health Sciences Turkey, Izmir Bozyaka Education and Research Hospital, Turkey.
  • Ahmet Deniz Ucar Department of General Surgery, University of Health Sciences Turkey, Izmir Bozyaka Education and Research Hospital, Turkey.
  • Sedat Tan Department of General Surgery, University of Health Sciences Turkey, Izmir Bozyaka Education and Research Hospital, Turkey.

DOI:

https://doi.org/10.36570/jduhs.2022.3.1659

Keywords:

Ampulla of Vater, Second Primary, Metachronous, Cancer, Multiple Primary Neoplasms

Abstract

Post-metachronous ampulla of Vater carcinoma after gastric cancer is an extremely rare between multiple primary cancers. The published literature contains only a few cases. Among the cases males are found more frequently. The majority of the cases reported after early gastric cancer. The main problem is to distinguish between new cancer and metastasis in gastric cancer patients. Early onset of jaundice, which is the main clinical finding, is important in diagnosis. The main type of surgery is pancreaticoduodenectomy. In this study, the clinic, diagnosis, and treatment of the post-metachronal ampulla of Vater cancer and the highlights of management options reviewed.

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References

Warren S, Gates O. Multiple primary malignant tumors: a survey of the literature and statistical study. Am J Cancer 1932; 61:1358-414.

Bae JS, Lee JH, Ryu KW, Kim YW, Bae JM.Characteristics of synchronous cancers in gastric cancer patients. Cancer Res Treat 2006; 38:25-9.

doi:10.4143/crt.2006.38.1.25

Lee JH, Bae JS, Ryu KW, Lee JS, Park SR, Kim CG, et al. Gastric cancer patients at high-risk of having synchronous cancer. World J Gastroenterol 2006; 12: 2588-92.

doi:10.3748/wjg.v12.i16.2588

Muela MA, Jorquera PF, Ribas AT, Malagon RR, Espinel DV, Ballesteros del RB, et al. Multiple malignant primary neoplasms in patients with gastric neoplasms in the health district of Leon. Rev Esp Enferm Dig 2006; 98:907–16.

doi:10.4321/s1130-01082006001200003

Dinis RM, Lomba VH, Silva R, Moreira L, Lomba VR. Associated primary tumours in patients with gastric cancer. J Clin Gastroenterol 2002; 34:533–5.

doi:10.1097/00004836-200205000-00010

Hayat MJ, Howlader N, Reichman ME, Edwards BK. Cancer statistics, trends, and multiple primary cancer analyses from the surveillance, epidemiology, and end results (SEER) program. Oncologist 2007; 12:20–37.

doi:10.1634/theoncologist.12-1-20

Lawniczak M, Gawin A, Jaroszewicz - Heigelmann H, Rogoza-Mateja W, Raszeja-Wyszomirska J, Bialek A, et al. Synchronous and metachronous neoplasms in gastric cancer patients: a 23-year study. World J Gastroenterol 2014; 20:7480.

doi:10.3748/wjg.v20.i23.7480

Eom B W, Lee HJ, Yoo M W, Cho J J, Kim W H, Yang H K, et al. Synchronous and metachronous cancers in patients with gastric cancer. J Surg Oncol 2008; 98:106-10.

doi: 0.1002/jso.21027

Kim JH, Rha SY, Kim C, Kim GM, Yoon SH, Kim KH, et al. Clinicopathologic features of metachronous or synchronous gastric cancer patients with three or more primary sites. Cancer Res Treat 2010; 42:217-24.

doi:10.4143/crt.2010.42.4.217

Park YK, Kim DY, Joo JK, Kim JC, Koh YS, Ryu SY, et al. Clinicopathological features of gastric carcinoma patients with other primary carcinomas. Langenbecks Arch Surg 2005; 390:300-5.

doi:0.1007/s00423-004-0525-4

Ikeda Y, Saku M, Kishihara F, Maehara Y. Effective follow up for recurrence or a second primary cancer in patients with early gastric cancer. Br J Surg 2005;92:235-9.

doi:10.1002/bjs.4758

Ikeda Y, Saku M, Kawanaka H, Nonaka M, Yoshida K. Features of second primary cancer in patients with gastric cancer. Oncology 2003; 65:113-7.

doi:10.1159/000072335

Marrano D, Viti G, Grigioni W, Marra A. Synchronous and metachronous cancer of the stomach. Eur J Surg Oncol 1987; 13:493-8.

Kim JY, Jang WY, Heo MH, Lee KK, Do YR, Park KU, et al. Metachronous double primary cancer after diagnosis of gastric cancer. Cancer Res Treat 2012; 44:173-8.

doi:10.3748/wjg.v20.i23.7480

Mafune K, Tanaka Y, Ma Y Y, Takubo K. Synchronous cancer of the esophagus and the ampulla of Vater after distal gastrectomy: successful removal of the esophagus, gastric remnant, duodenum, and pancreatic head. J Surg Oncol 1995; 60:277-81.

doi:10.1002/jso.2930600412

Sawada T, Muto T. Familial adenomatous polyposis: should patients undergo surveillance of the upper gastrointestinal tract? Endoscopy 1995; 27:6-11.

doi:10.1055/s-2007-1005625

Tomita H, Fukunari H, Shibata M, Yoshinaga K, Iwama T, et al. Ampullary carcinoma in familial adenomatous polyposis: report of a case. Surg Today 1996; 26:522-6.

doi:10.1007/BF00311560

Karayiannakis AJ, Kakolyris S, Kouklakis G, Xenidis N, Bolanaki H, Tsalikidis C. Synchronous carcinoma of the ampulla of vater and colon cancer. Case Rep Gastroenterol 2011; 5:301–7.

doi:10.1159/000329344

Green PH, O Toole KM, Weinberg LM, Goldfarb JP. Early gastric cancer. Gastroenterology 1981; 81:247-56.

Lan YT, Lin JK, Li AF, Lin TC, Chen WS, Jiang JK, et al. Metachronous colorectal cancer: Necessity of post-operative colonoscopic surveillance. Int J Colorectal Dis 2005; 20:121-5.

doi:10.1007/s00384-004-0635-z

Wu CW, Lo SS, Chen JH, Hsieh MC, Li AF, Lui WY. Multiple primary cancers in patients with gastric cancer. Hepatogastroenterology 2006; 53:463-7.

Ahn DH, Bekaii-Saab T. Ampullary cancer: An overview. Am Soc Clin Oncol Educ Book 2014; 112.

doi:10.14694/EdBook_AM.2014.34.112

Pea A, Riva G, Bernasconi R, Sereni E, Lawlor RT, Scarpa A, et al. Ampulla of Vater carcinoma: Molecular landscape and clinical implications. World J Gastrointest Oncol 2018;10:370-80.

doi:10.4251/wjgo.v10.i11.370

de Castro SM, van Heek NT, Kuhlmann KF, Busch OR, Offerhaus GJ, van Gulik TM, et al. Surgical management of neoplasms of the ampulla of Vater: local resection or pancreatoduodenectomy and prognostic factors for survival. Surgery 2004; 136:994-1002.

doi:10.1016/j.surg.2004.03.010

Defrain C, Chang CY, Srikureja W, Nguyen PT, Gu M. Cytologic features and diagnostic pitfalls of primary ampullary tumors by endoscopic ultrasound-guided fine-needle aspiration biopsy. Cancer 2005; 105:289-97.

doi:10.1002/cncr.21306

Yoshizumi M, Sato T, Kunii Y, Kamata T. Case of metachronous double cancer in the papilla vateri and the stomach with an interesting clinical course. Gan No Rinsho 1968; 14:816-9.

Ozeki Y, Onitsuka A, Hayashi M, Hirose M, Shimokawa K. Metachronous double cancer of the stomach and papilla of vater -a case report- J Jap Pract Surg Soc 1988; 49:310-5.

doi:10.3919/ringe1963.49.310

Akiyama N, Ishizaki M,Tanaka S, Fujita K. A case of fam-ilial adenomatous polyposis associated with multiple colon cancers,early gastric cancer and cancer of the major papilla.Nippon Rinsho Geka Gakkai Zasshi(J Japan Surg Assoc) 2000; 61:161-7.(in Japanese)

doi:10.3919/JJSA.61.1613

Eriguchi N, Aoyagi S, Tamae T, Nishimura K, Hamada S, Kawabata M, et al. Carcinoma of the ampulla of Vater associated with other organ malignancies. Kurume Med J 2001; 48:255-9.

doi:10.2739/kurumemedj.48.255

Kim C. Clinicopathologic characteristics of second prim-ary cancers in patients with gastric cancer. The master's thesis. Department of Medicine, the Graduate School, Yonsei University, S. Korea 2005.

Woo SM, Ryu JK, Lee SH, Lee WJ, Hwang JH, Yoo JW, et al. Feasibility of endoscopic papillectomy in early stage ampulla of Vater cancer. J Gastroenterol Hepatol 2009; 24:120-4.

doi:10.1111/j.1440-1746.2008.05578.x

Hatzaras I, George N, Muscarella P, Melvin W S, Ellison EC, Bloomston M, et al. Predictors of survival in peri-ampullary cancers following pancreatico-duodenectomy. Ann Surg Oncol 2010; 17:991-7.

doi:10.1245/s10434-009-0883-9

Riall TS, Cameron JL, Lillemoe KD, Winter JM,Campbell KA, Hruban RH, et al. Resected periampullary adenocarci - noma: 5-year survivors and their 6- to 10-year follow-up. Surgery 2006; 140:764-72.

doi:10.1016/j.surg.2006.04.006

Kim JH, Kim JH, Han JH, Yoo BM, Kim MW, Kim W H. Is endoscopic papillectomy safe for ampullary adenomas with high grade dysplasia? Ann Surg Oncol 2009;16: 2547-54.

doi:10.1245/s10434-009-0509-2

Kobayashi A, Konishi M, Nakagohri T, Takahashi S, Kinoshita T. Therapeutic approach to tumors of the ampulla of Vater. Am J Surg 2006; 192: 161-4.

doi:10.1016/ j.amjsurg.2006.05.002

Kimura W, Futakawa N, Yamagata S, Wada Y, Kuroda A, Muto T, et al. Different clinicopathologic findings in two histologic types of carcinoma of papilla of Vater. Jpn J Cancer Res 1994; 85:161-6.

doi:10.1111/j.1349-7006.1994.tb02077.x

Jung S, Kim MH, Seo DW, Lee SK.Endoscopic snare papillectomy of adenocarcinoma of the major duodenal papilla. Gastrointest Endosc 2001; 54:622.

doi:10.1067/mge.2001.117765

Lee J H, Whittington R, Williams N N, Berry MF, Vaughn DJ, Haller DG, et al. Outcome of pancre-aticoduoden-ectomy and impact of adjuvant therapy for ampullary carcinomas. Int J Radiat Oncol Biol Phys 2000; 47:945–53.

doi:10.1016/s0360-3016(00)00537-x

Sikora SS, Balachandran P, Dimri K, Rastogi N, Kumar A,

Saxena R, et al. Adjuvant chemoradiotherapy in ampu-llary cancers. Eur J Surg Oncol. 2005; 31:158–63.

doi:10.1016/j.ejso.2004.08.013

Bhatia S, Miller RC, Haddock MG, Donohue JH, Krişhan S. Adjuvant therapy for ampullary carcinomas: the Mayo Clinic experience. Int J Radiat Oncol Biol Phys 2006; 66:514–9. doi:10.1016/j.ijrobp.2006.04.018

Winter JM, Cameron JL, Olino K, Herman JM, de Jong MC, Hruban RH, et al. Clinicopathologic analysis of ampullary neoplasms in 450 patients: implications for surgical strategy and long-term prognosis. J Gastrointest Surg 2010; 14:379-87.

doi:10.1007/s11605-009-1080-7

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Published

2022-10-21

How to Cite

Yildirim, M., Oymaci, E., Ucar, A. D., & Tan, S. (2022). Post-Metachronous Cancer of the Ampulla of Vater after Gastric Cancer Surgery: An Overview. Journal of the Dow University of Health Sciences (JDUHS), 16(3), 145–150. https://doi.org/10.36570/jduhs.2022.3.1659

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Review Article