Genetic Diversity and Comprehensive Phylodynamic Analysis of Whole Corona Viruses Genomes

Authors

  • Shehla Javaid University Institute of Medical Lab Technology, University of Lahore, Lahore, Pakistan
  • Hina Awais University Institute of Medical Lab Technology, University of Lahore, Lahore, Pakistan

Keywords:

COVID-19, Phylogeny, SARS-CoV, MERS-CoV, Coding Sequence(CDS)

Abstract

Covid-19 is a rapidly emerging viral respiratory disease. The infection of corona virus disease (COVID-19) is initiated by the strains of severe acute respiratory syndrome. Corona virus 2 (SARS-CoV-2), is a highly transmittable viral infection that was first emerged in the of Wuhan, a city of China and ultimately extent in whole world. The World health organization (WHO) affirmed this infection as a global public health disaster. Genomic analysis showing that this novel SARSCoV-2 is hereditarily linked with severe acute respiratory syndrome-like (SARS-like) bat viruses indicating that bats might be the primary source of this epidemic infection. In this review we have summarized a comprehensive phylodynamic analysis of whole corona virus genome sequences in order to analyze the pathogenicity and emergence of novel COVID-19 infection and previous human coronaviruses. Our main objective is to describe the genetic relationships of the 2019-nCoV with other genera of coronavirus and to find out supposed recombination contained by sarbecovirus subgenus. Keywords: COVID-19, Phylogeny, SARS-CoV, MERS-CoV, Coding Sequence (CDS).

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Published

2021-04-06 — Updated on 2022-01-15

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How to Cite

Javaid, S., & Awais, H. (2022). Genetic Diversity and Comprehensive Phylodynamic Analysis of Whole Corona Viruses Genomes. Journal of the Dow University of Health Sciences (JDUHS), 15(1), 41–45. Retrieved from https://mail.jduhs.com/index.php/jduhs/article/view/1112 (Original work published April 6, 2021)

Issue

Vol. 15 No. 1

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Commentary

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